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Educational Curriculum

The Internal Review Board extends guidance and support to fellows with their research activities.  A designated Research Director is available to guide and assist fellows. The Medical Center sponsors an annual Research Day that welcomes presentation from faculty and fellows. On site librarians offer personalized assistance with literature searches, inter library loan and reference services. Well-appointed computer terminals are available to faculty, fellows and employees. Fellows receive a generous educational stipend for conference attendance and reimbursement for books, journals, dues and technology.

PATIENT CARE

 

  1. Is able to demonstrate during inpatient rotations compassionate care concerning problems (pain, nutrition, depression).
  1. Management of Leukemic Patients
    1. To identify which patients need treatment.
    2. To understand the different treatments for different Leukemias
    3. To know the induction chemotherapy and consolidation therapy of ALL and ANLL.
    4. To know indications of bone marrow transplant in various Leukemias
    5. To be able to manage emergencies like Tumor Lysis Syndrome
    6. To manage complications of chemotherapy in Leukemic patients
    7. To be able to give intrathecal chemotherapy
    8. To understand the indications for transfusion support and the appropriate blood products to utilize in patients with leukemia
  1. General Evaluation of Lymphomas
    1. To be able to evaluate patients with Lymphadenopathy
    2. Know the pitfalls of fine needle aspiration and the importance of obtaining an excisional biopsy in the diagnosis of lymphoma
    3. Understand the difference between Hodgkin’s Disease (HD) and Non-Hodgkin’s Lymphomas (NHL) in presentation, diagnosis and treatment
  1.  Oncologic Emergencies

a.       Recognize the signs and symptoms of hypercalcemia and be able to treat

    1. Understand the symptoms and the appropriate diagnostic procedures for diagnosing spinal cord compression
    2. Understand which patients should receive emergent radiotherapy and which patient should undergo laminectomy for treatment of spinal cord compression
    3. Be able to recognize Tumor Lysis Syndrome and know how to manage
    4. Recognize the signs and symptoms of Superior Vena Cava Syndrome, and utilize appropriate diagnostic testing and management

MEDICAL KNOWLEDGE

  1. Understanding of Molecular Biology of Cancer (Lectures, molecular Biology Rotation).

.

  1. Molecular Biology and Gene Regulation:
    1. Understand the structure of DNA
    2. Understand the techniques for DNA analysis and their applications e.g. PCR
    3. Understand what oncogenes are and their role in tumorigenesis
    4. Know how gene expression is controlled
    5. List known tumor suppressor genes and their associated tumors
  1. Cell Proliferation:
    1. Know the different phases of the cell cycle
    2. Know what oncogenes are involved in cell cycle progression
    3. Know how tumor suppressor genes effect the cell cycle
  1. Epidemiology of Cancer (Lecture Series, Clinics)
  2. Carcinogenesis:
  3. Describe the genetic and environmental factors and their interactions which lead to the development of cancer
  1. Cancer Prevention:
  2. Describe what types of primary prevention are currently available.
  3. Understand situations where there might be a role for prophylactic surgery
  4. Understand the strategy of chemoprevention trials
  5. Demonstrate knowledge of current screening procedures and their sensitivity, specificity and cost effectiveness
  6. Counsel patients in their risk for development of cancer
  1. Clinical Pharmacology (Basic Science Lectures, Oncology Inpatient and Clinics)
  2. Pharmacokinetics:
  3. Understand the absorption, distribution and elimination of chemotherapeutic agents
  4. Methods of Delivery:
  5. Demonstrate the administration of intravenous chemotherapy
  6. List chemotherapeutic agents which are vesicants and explain how to manage drug extravasation
  7. Demonstrate use of in-dwelling catheters, e.g. porta Cath, Hickman
  8. Demonstrate the delivery of intrathecal chemotherapy and describe toxicity
  9. Understand the expected short toxicities of individual agents
  10. Manage toxicities in patients receiving chemotherapy including emesis, cytopenias, etc.
  11. List the long term toxicities of single and combined chemotherapeutic regimens.
    1. New agents
    2. Drug Resistance
  1. Radiation Therapy – See RT Elective Goals and Objectives
  1. Bone Marrow Transplantation – See BMT Elective Goals and Objectives
  1. Leukemia (Ward experience, blood bank and flow cytometry rotations, morphology

sessions).

  1. To know the difference between various types of leukemia.
  1. Diagnosis:
  1. To make a peripheral smear and identify different types of leukemia’s by morphology
  2. To be able to do a bone marrow aspiratory, bone marrow biopsy and touch preparation and core biopsy of the bone
  3. To know what special studies need to be done on peripheral blood or bone marrow aspirate samples of Leukemia patients i.e. cytogenetics, flow cytometry, etc.
  4. To do spinal tap and interpret CSF cytology for diagnosis of Leukemic Meningitis
  1. Clinical Features:
  2. To know and identify clinical syndromes associated with specific leukemia’s e.g. DIC in APL, hemolytic anemia in CLL, etc.
  3. To identify the Prognosis of various leukemia.
  1. Lymphomas (Oncology inpatient, clinics, tumor board, lectures)
  2. Pathology
  3. Be able to identify Reed Sternberg cells.
  4. Know the importance of flow cytometry and cytogenetics in establishing the diagnosis and prognosis of lymphomas.
  1. Staging
  2. Be able to stage lymphomas according to Ann Arbor classification
  3. Know the Cotswold modification of the Ann Arbor staging
  4. Know the appropriate use of radiographic and radio nucleotide studies for staging purposes.
  5. Know the indications for lumbar puncture in patients with NHL.
  1. Treatment
  2. Know the standard chemotherapeutic regimens used for treatment of HD and NHL
  3. Demonstrate appropriate management of patients with massive mediastinal HD
  4. Know the indications of treatment of NHL
  5. Be able to diagnose and manage Tumor Lysis Syndrome.
  6. Demonstrate administration of intrathecal chemotherapy
  1. Carcinoma of the Breast (Oncology rotations, clinics, radiation elective)
  2. Epidemiology:
  3. State the risk factors for the development of breast cancer
  4. Be able to counsel patients about their risk factors for future breast cancer and other cancers
  5. Be able to counsel family members about their risk
  1. Diagnosis:
  2. State the ACS recommendations for the use of screening mammography.
  3. Describe the role of ultrasonography for diagnosis of breast mass
  4. Be able to demonstrate physical examination of the breast and axilla. Teach patient self-breast examinations
  5. Discuss the indications for biopsy of breast mass
  6. Discuss the indications for fine needle aspiration of a breast mass
  1. Staging and Prognostic Features:
  2. State the staging utilizing in the TNM classification
  3. Describe the different prognostic features which identify and increased risk for recurrence of breast cancer
  4. Demonstrate the use of appropriate diagnostic tests for staging of breast cancer including pre surgical evaluation
  1. Gastrointestinal Cancers (Inpatient and outpatient rotations, RT elective)
  2. Colorectal Cancer:
  3. Discuss the staging of colorectal cancer and risk factors for development, environmental and genetic
  4. Understand the use of CEA in follow of patient
  5. Demonstrate the appropriate staging work up
  6. Describe the role of post-operative RT in rectal cancer
  7. Know which patient benefit from adjuvant chemotherapy and the regimens employed
  8. Know the chemotherapeutic regimens utilized for treatment of metastatic disease
  1. Esophageal Cancer:
  2. Understand the benefits and toxicities of combine modality therapy
  3. Understand the importance of nutritional support in esophageal cancer and the techniques employed, e.g. Hyper alimentation with PEG, gastrostomy, TPN, PPN
  1. Gastric Cancer
  2. Describe the risk factors for development of gastric carcinoma
  3. Understand the pattern of spread
  4. Utilize the appropriate non-invasive tests for diagnosis and staging
  5. Understand the surgical management of primary disease
  6. Understand the role of chemotherapy in advance disease
  1. Pancreatic Cancer:
  2. Utilize the appropriate non-invasive procedures for diagnosis
  3. Describe the role of the Whipple’s procedure in primary management
  4. Understand the use of radiation therapy in management
  5. Describe palliative surgical procedures
  6. Discuss the use of 5FU as a radiation sensitizer and its use a primary treatment
  7. Understand new chemotherapeutic agents in management of pancreatic cancer
  1. Hepatocellular Cancer:
  2. Define the risk factors for the development of hepatocellular cancer
  3. Understand which patients may benefit from surgery
  4. Describe the use of hepatic artery infusion
  5. Know what chemotherapy is active in treatment of hepatoma
  1. Renal Cancer:
  2. List the risk factors for the development of renal cancer
  3. Recognize the clinical presentation of kidney cancer and the common sites of metastases
  4. Describe the radiographic tool utilized to diagnose hyper leproma
  5. Know the staging and prognosis of kidney cancer
  6. Recognize which patients are surgical candidates
  7. Describe role of radiation therapy in the management
  8. Understand the role of biologic response modifiers in treatment
  1. Gynecologic Malignancies (Gyn elective, oncology inpatients, clinics, RT elective)
  2. Ovarian Cancer:
    1. Epidemiology: Know the risk factors for ovarian cancer – isolated and familial
    2. Diagnosis and Staging:
      1. Know the signs and symptoms
      2. Know the significance of tumor markers and the role of CA-125 in screening.
      3. Understand the evaluation and management of an adnexal mass
      4. Know the FIGO staging of ovarian cancer
      5. Management:
    3. Know the standard surgical treatment and importance of debunking
    4. Know the stages which require chemotherapy and which

Chemotherapeutic agents to use

  1. Know the indications of radiation treatment for different stages of disease
  2. Know the significance and importance of a second look laparotomy
  3. Know the management of recurrent disease

b. Endometrial Cancer:

1.  Know the importance of different risk factors and the association

between tamoxifen and endometrial cancer.

  1. Describe the clinical presentation and the appropriate diagnostic

procedures

  1. Know the FIGO staging
  2. Understand the management of the different stages and the role of surgery, radiation therapy and chemotherapy
  3. Understand the management of recurrent disease
  4. Know the management of uterine sarcoma
  1. Lung Cancer (Tumor boards, outpatient and inpatient rotations, RT elective)
  2. Non-small Cell Carcinoma:
  3. Know how to evaluate a solitary pulmonary nodule
  4. Know the appropriate methods for obtaining a tissue diagnosis
  5. Describe the TMN staging of NSCLC
  6. Understand which patients are primary surgical candidates
  7. Understand the role of radiotherapy in the management of NSCLC
  8. Know which chemotherapeutic agents are active in lung cancer
  9. Discuss the role of neoadjuvant chemotherapy in NSCLC
  10. Know the prognosis of patients after primary therapy
  11. Be able to provide palliative care for patients with metastatic disease
  1. Small Cell Carcinoma:
  2. Demonstrate the use of appropriate diagnostic and staging procedures
  3. Discuss the prognostic differences between limited and extensive disease
  4. Understand the role of multimodality therapy, i.e. radiotherapy and chemotherapy
  5. Discuss the controversy about the role of prophylactic cranial irradiation
  1. Complications of Malignancy (Lecture series, oncology rotation)
  2. Complications of Treatment:
  3. Demonstrate understanding of acute toxicities of chemotherapeutic agents and the management of toxicities
  4. Describe how combined radiation and chemotherapy lead to enhanced toxicities
  5. Describe the situations in which secondary hematologic malignancies and myelodysplastic syndromes arise
  6. Describe situations in which secondary solid tumors occur
  7. Understand late effects that occur after whole brain irradiation
  1. Pain Management – See Pain Management Elective Goals and Objectives
  1. Neutropenic Fever:

1.      Understand the common organisms which cause infection in the febrile neutropenic patient

  1. Know when and which antibiotics to start
  2. Understand the use of growth factors in the management of the neutropenic patient
  3. Know when to utilize antifungal therapy

PRACTICE BASED LEARNING

 

  1.  Regularly self-assesses his opinion on new patients and the opinion of the teaching faculty.
  1.   Looks at literature to decide on controversial issues

INTERPERSONAL SKILLS AND COMMUNICATIONS

  1. Be aware of community support groups
  2. Understand when patients require medical treatment to manage depression, etc.

PROFESSIONALISM

 

  1. Be able to demonstrate a commitment to patients from diverse ethnic and educational levels
  1. Responds appropriately to constructive criticism
  1. Demonstrates on “360” evaluations a thorough commitment to ethical

principals for our demographically diverse patient population

SYSTEM BASED PRACTICE

  1. Actively participates in rounds with the attending hematology/oncologists and Inter Hospital Conferences

{tab PGY 5}

PATIENT CARE

  1. Management of Leukemic Patients
    1. To identify which patients need treatment
    2. To know the difference of treatment between the different leukemia’s
    3. To know the management of refractory and relapsed Leukemia’s

.

  1. Local Treatment of Breast Cancer
  2. Counsel patients about the option of surgical management of primary tumor. Be able to describe modified radical mastectomy as compared to breast-conserving surgery with axillary dissection
  3. Identify patients who require local postoperative breast irradiation
  4. Counsel patients about the use of breast reconstructive surgery
  5.      Identify patients who should receive neoadjuvant chemotherapy.

MEDICAL KNOWLEDGE

  1. Understanding of Molecular Biology of Cancer (Lectures, molecular Biology Rotation).
  2. Growth Factors:
    1. Recognize which oncogenes are associated with growth factors
    2. List known growth factors, their sources and their target cells
    3. List Growth inhibitory cytokines
  1. Chromosomal Abnormalities:
  2. List the known chromosomal abnormalities associated with

malignancies

  1. Describe the different methods of identifying chromosomal

deletions, inversions, translocations and duplications

  1. Demonstrate the application of chromosome analysis in the

    management of malignancies

  1. Clinical Pharmacology (Basic Science Lectures, Oncology Inpatient and Clinics)
  2. Pharmacokinetics:
  3. Describe dose-response curves and the factors that influence

pharmacodynamics

  1. Methods of Delivery:
  2.     Describe the use of intra pleural and intraperitoneal chemotherapy
  3. Discuss the factors involved in determination of the schedule of

administration of chemotherapy

  1. Define neoadjuvant chemotherapy, potential advantages and

the disadvantages

  1. Toxicity:
  1. Radiation Therapy – See RT Elective Goals and Objectives
  1. Biologic Response Modifiers (Clinical Rotations)
    1. Describe the pharmacology of the different biologics
    2. Demonstrate an understanding of the role of biologic therapy in the management of solid tumors and lymphoproliferative disorders
    3. Describe the potential use and disadvantages of monoclonal antibodies
  1. Bone Marrow Transplantation – See BMT Elective Goals and Objectives
  1. Research – design and conduct of clinical trials (Journal Club, Dr. Debari’s course,

Review of Clinical Trials)

  1. Demonstrate an understanding of the different types of clinical trials utilized
  2.     Demonstrates an understanding of the descriptive terminology utilized in

both epidemiologic treatment trials and statistical analyses

  1.    Understand what the endpoints are of different clinical trials
  2.     Understand what size and duration of study are necessary to reach

statistical significance

  1.    Demonstrate a knowledge of the need for informed consent
  2. Understand the usefulness and limitations of meta-analyses
  1. Leukemia’s (Ward experience, blood bank and flow cytometry rotations, morphology sessions).
  2. To know the difference between various types of Leukemia’s.
  3. Diagnosis:
  1. To know different cyto chemical stains used to evaluate Leukemia’s and interpret them.
  2. To be able to interpret flow cytometry results.
  3. To know the characteristic cytogenetic abnormalities of different leukemia’s and their significance.
  4. To be able to interpret bone marrow aspirate smear morphology and differentiate between various Leukemia’s.

            

  1. Lymphomas (Oncology inpatient, clinics, tumor board, lectures)
  2. Pathology
  3. Know the difference pathological classification of NHL and their clinical significance.
  4. Prognosis
  5. Know the various prognostic factors in HD and NHL.
  6. Know the prognostic significance of cytogenetic abnormalities and immunophenotyping.
  1. Treatment
  2. Be able to decide the type of treatment modality (RT versus chemotherapy) in the treatment of HD
  3. Know the indications for ABMT and peripheral stem cell transplantation in HD and NHL
  4. Be able to appropriately recognize and treat both infectious and immunological complications of bone marrow transplant
  1. Carcinoma of the Breast (Oncology rotations, clinics, radiation elective)
  2. Diagnosis:
  3. State the ACS recommendations for the use of screening mammography
  4. Describe the role of ultrasonography for diagnosis of breast mass
  5. Be able to demonstrate physical examination of the breast and axilla. Teach a patient self-breast examination
  6. Discuss the indications for biopsy of breast mass
  7. Discuss the indications for fine needle aspiration of a breast mass
  1. Staging and Prognostic Features:
  2. Describe the use of tumor markers, CEA and CA 15-3, for diagnosis and follow up of patients
  1. Gastrointestinal Cancers (Inpatient and outpatient rotations, RT elective)
  1. Esophageal Cancer:
  2. Understand the benefits and toxicities of combine modality therapy
  3. Understand the importance of nutritional support in esophageal cancer and the techniques employed, e.g. Hyper alimentation with PEG, gastrostomy, TPN, PPN
  1. Gastric Cancer
  2. Describe the risk factors for development of gastric carcinoma
  3. Understand the pattern of spread
  4. Utilize the appropriate non-invasive tests for diagnosis and staging
  5. Understand the surgical management of primary disease
  6. Understand the role of chemotherapy in advance disease
  1. Pancreatic Cancer:
  2. Utilize the appropriate non-invasive procedures for diagnosis.
  3. Describe the role of the Whipple’s procedure in primary management
  4. Understand the use of radiation therapy in management
  5. Describe palliative surgical procedures
  6. Discuss the use of 5FU as a radiation sensitizer and its use a primary treatment
  7. Understand new chemotherapeutic agents in management of pancreatic cancer
  1. Hepatocellular Cancer:
  2. Define the risk factors for the development of hepatocellular cancer
  3. Understand which patients may benefit from surgery
  4. Describe the use of hepatic artery infusion
  5. Know what chemotherapy is active in treatment of hepatoma
  1. Anal Cancer:
  2. List risk factors and histopathologic subtypes of anal cancer
  3. Know the appropriate staging procedures
  4. Describe the surgical management and the role of radiation therapy
  5. Understand the benefits of multimodality therapy including chemotherapy
  1. Neuroendocrine Tumors:
  2. Describe the clinical syndromes associated with carcinoid tumors and pheochromocytomas.
  3. Recognize the sites of origin of neuroendocrine tumors.
  4. Understand the role of surgery and chemotherapy in management.
  5. Describe palliative treatment options.
  1. Genitourinary Tract Cancer (inpatient and outpatient rotations, RT elective)
  2. Testicular Cancer:
  3. Be able to recognize clinical presentation
  4. Describe histopathology
  5. Be able to utilize tumor markers for clinical stating in non seminomatous tumors
  6. Perform appropriate noninvasive imaging for post-orchiectomy staging
  7. Understand the role of retroperitoneal lymph node dissection vs. surveillance
  8. Define the role of RT in post-op management of seminars.
  9. Describe which patients with pure seminomas require chemotherapy
  10. Be able to list poor prognostic features associated with non-siminomatous tumors and utilize this to select appropriate chemotherapy
  11. Understand management of patients with PR or recurrent disease
  12. Describe complications of disease and treatment e.g. vascular, bleomycin pulm toxicity
  1. Bladder Cancer:
  2. List risk factors for development of bladder cancer
  3. Describe the roles of surgery and intravesical treatment for patients with superficial bladder cancer
  4. Understand the surgical management of invasive cancer
  5. Understand the role of pre-and/or post-op radiation therapy
  6. Identify the patients who are appropriate candidates for neoadjuvant chemotherapy
  7. Understand the active chemotherapeutic regimens for metastatic disease and their response rates
  1. Prostate Cancer:

1.      Understand the use of PSA screening

  1. Understand the staging and histologic classification
  2. Utilize approach staging tests
  3. Identify patients who are appropriate for surgical management
  4. Describe the toxicities associated with total prostatectomy
  5. Describe the toxicity of radiation therapy
  6. Understand the role of hormone therapy in the management of prostate cancer and the available hormone manipulations
  7. Describe the pattern of metastasis
  1. Gynecologic Malignancies (Gyn elective, oncology inpatients, clinics, RT elective)
  2. Ovarian Cancer:
  3. Management:
    1. Know the standard surgical treatment and importance of debunking
    2. Know the stages which require chemotherapy and which
    3. Chemotherapeutic agents to use
    4. Know the indications of radiation treatment for different stages of disease
    5. Know the significance and importance of a second look laparotomy
    6. Know the management of recurrent disease

b. Endometrial Cancer:

1.   Know the importance of different risk factors and the association

between tamoxifen and endometrial cancer

  1. Describe the clinical presentation and the appropriate diagnostic

procedures

  1.    Know the FIGO staging
  2.     Understand the management of the different stages and the

role surgery, radiation therapy and chemotherapy

  1. Understand the management of recurrent disease
  1. Know the management of uterine sarcoma

d. Cervical Cancer:

1.      Know the risk factors and the importance of herpes simplex virus and human papilloma virus

  1. Know the natural history and the patterns of spread
  2. Know the diagnostic procedures and the importance of screening (PAP)
  3. Know the standard clinical evaluation needed for preop staging
  4. Know the FIGO staging of cervical cancer
  5. Understand the management of the different stages of disease and the role of radiation and surgery
  6. Understand the techniques and doses of radiation utilized in treatment
  7. Describe the expected response rates with chemotherapy and its role of palliative management
  1. Head and Neck Cancer (Lectures, outpatient clinics, RT elective, tumor board)
  2. Squamous Cell Carcinoma:

1.    Understand the anatomy and the different sites of origin of

carcinoma

2.      Demonstrate the use of appropriate staging in the management.

3.    Know the roles of surgery and radiation in each of the different subtypes

  1. Understand the risks and benefits of larynx sparing surgery
  2. Understand the role of neoadjuvant chemotherapy
  1. Thyroid Cancer:
  2. Understand the incidence and classification of thyroid cancer
  3.    Know the TNM staging
  4. Know the risk factors for the development of thyroid cancer e.g.

goiter, RT

  1. Demonstrate how to evaluate a thyroid nodule with nonnative testing and use of FNA
  2. Understand how to manage patients with well-differentiated thyroid cancer and the prognosis (surgery, suppression, I-131).
  1. Sarcomas/Mesothelioma (Outpatient and inpatient rotations)
  2. Mesothelioma:
  3. Understand the association with asbestos and who is at risk for mesothelioma
  4. Know what biopsy procedures are available for diagnosis
  5. Understand the role of surgery, RT and chemotherapy in the management and the prognosis
  1. Melanoma (Outpatient rotations)
    1. List the risk factors for development of malignant melanoma
    2. Describe the different histologic subtypes of melanoma
    3. Understand the different staging systems – Clark, Breslow
    4. Define the prognostic features
    5. Understand the surgical management of melanoma
    6. Discuss the role of elective lymph node dissection
    7. Understand the role of adjuvant therapy
    8. Understand the different treatment modalities for metastatic disease including chemotherapy, radiation therapy, hormone therapy, biologic response modifiers, and adoptive immunotherapy and tumor vaccines
  1. Complications of Malignancy (Lecture series, oncology rotation)
  1. Hospice – See Hospice Elective Goals and Objectives
  1. Pain Management – See Pain Management Elective Goals and Objectives
  1. Neutropenic Fever:

1.      Understand the common organisms which cause infection in the febrile neutropenic patient

  1. Know when and which antibiotics to start
  2. Understand the use of growth factors in the management of the neutropenic patient
  3. Know when to utilize antifungal therapy

PRACTICE BASED LEARNING

 

  1. Regularly self-assesses his opinion on new patients and the opinion of the teaching faculty
  2. Looks at literature to decide on controversial issues

 

 

INTERPERSONAL SKILLS AND COMMUNICATIONS

  1. Demonstrate to teaching faculty an ability to honestly and in lay terms explain

the prognosis to patients

  1. Perform a psychosocial assessment of patients with cancer
  2. Participate in counseling sessions attended by patients, family members and

psychosocial professionals

  1. Know how to utilize appropriate resources to assist patients and their families

with coping

PROFESSIONALISM

 

  1. Be able to demonstrate a commitment to patients from diverse ethnic and

educational levels

  1. Responds appropriately to constructive criticism
  2. Demonstrates on “360” evaluations a thorough commitment to ethical

principals for our demographically diverse patient population

SYSTEM BASED PRACTICE

  1. Actively participates in rounds with the attending hematology/oncologists

and Inter Hospital Conferences

{tab PGY-6}

PATIENT CARE

  1. Management of Leukemic Patients
  2. To identify which patients need treatment
  3. To know the difference of treatment between the different Leukemia’s
  4. To know the management of refractory and relapsed Leukemia’s

MEDICAL KNOWLEDGE

  1. Understanding of Molecular Biology of Cancer (Lectures, molecular Biology Rotation).
  1. Chromosomal Abnormalities:
  • List the known chromosomal abnormalities associated with malignancies
  • Describe the different methods of identifying chromosomal deletions, inversions, translocations and duplications
  • Demonstrate the application of chromosome analysis in the management of malignancies
  1. Clinical Pharmacology (Basic Science Lectures, Oncology Inpatient and Clinics)
  2. Pharmacokinetics:
  1. Describe dose-response curves and the factors that influence pharmacodynamics
  2. Methods of Delivery:
  3. Describe the use of intrapleural and intraperitoneal chemotherapy
  4. Discuss the factors involved in determination of the schedule of administration of chemotherapy
  5. Define neoadjuvant chemotherapy, potential advantages and the disadvantages
    1. Toxicity:
    2. Define the mechanisms of drug resistance and associate with

individual drugs

  1. Describe new modalities for overcoming drug resistance
  1. Radiation Therapy – See RT Elective Goals and Objectives
  1. Biologic Response Modifiers (Clinical Rotations).
  1. Describe the pharmacology of the different biologics
  2. Demonstrate an understanding of the role of biologic therapy in the management of solid tumors and lymphoproliferative disorders
  3. Describe the potential use and disadvantages of monoclonal antibodies
  4. Bone Marrow Transplantation – See BMT Elective Goals and Objectives
  1. Research – design and conduct of clinical trials (Journal Club, Dr. Debari’s course,

Review of Clinical Trials)

  1. Demonstrate an understanding of the different types of clinical trials utilized
  2.     Demonstrates an understanding of the descriptive terminology utilized in

both Epidemiologic treatment trials and statistical analyses

  1. Understand what the endpoints are of different clinical trials
  2. Understand what size and duration of study are necessary to reach

statistical significance

  1. Demonstrate knowledge of the need for informed consent
  2.    Understand the usefulness and limitations of meta-analyses
  1. Leukemias (Ward experience, blood bank and flow cytometry rotations, morphology

sessions)

  1. To know the difference between various types of Leukemia’s
  1. Diagnosis:
  2. To be able to interpret flow cytometry results
  3. To know the characteristic cytogenetic abnormalities of different

Leukemia’s and their significance

  1. To be able to interpret bone marrow aspirate smear morphology and

differentiate between various Leukemia’s

            

  1. Lymphomas (Oncology inpatient, clinics, tumor board, lectures)
  2. Pathology
  1. Know the difference pathological classification of NHL and their clinical significance
  1. Prognosis
  2. Know the impact of histological grade on prognosis
  1. Treatment
  2. Be able to decide the type of treatment modality (RT versus chemotherapy) in the treatment of HD
  3. Know the indications for ABMT and peripheral stem cell transplantation in HD and NHL
  4. BE able to appropriately recognize and treat both infectious and immunological complications of bone marrow transplant
  5. Understand the long term complications (benign and malignant) seen in patients with HD treatment with RT, chemotherapy or both
  1. Gastrointestinal Cancers (Inpatient and outpatient rotations, RT elective)
  1. Esophageal Cancer:
  2. Understand the benefits and toxicities of combine modality therapy
  1. Understand the importance of nutritional support in esophageal cancer and

the techniques employed, e.g. Hyper alimentation with PEG, gastrostomy

TPN, PPN.

  1. Gastric Cancer
  2. Describe the risk factors for development of gastric carcinoma
  3. Understand the pattern of spread
  4. Utilize the appropriate non-invasive tests for diagnosis and staging
  5. Understand the surgical management of primary disease
  6. Understand the role of chemotherapy in advance disease
  1. Pancreatic Cancer:
  2. Utilize the appropriate non-invasive procedures for diagnosis
  3. Describe the role of the Whipple’s procedure in primary management
  4. Understand the use of radiation therapy in management
  5. Describe palliative surgical procedures
  6. Discuss the use of 5FU as a radiation sensitizer and its use a primary treatment
  7. Understand new chemotherapeutic agents in management of pancreatic cancer
  1. Hepatocellular Cancer:
  2. Define the risk factors for the development of hepatocellular cancer
  3. Understand which patients may benefit from surgery
  4. Describe the use of hepatic artery infusion
  5. Know what chemotherapy is active in treatment of hepatoma.
  1. Anal Cancer:
  2. List risk factors and histopathologic subtypes of anal cancer
  3. Know the appropriate staging procedures
  4. Describe the surgical management and the role of radiation therapy
  5. Understand the benefits of multimodality therapy including chemotherapy
  1. Neuroendocrine Tumors:
  2. Describe the clinical syndromes associated with carcinoid tumors and pheochromocytomas
  3. Recognize the sites of origin of neuroendocrine tumors
  4. Understand the role of surgery and chemotherapy in management
  5. Describe palliative treatment options
  1. Genitourinary Tract Cancer (inpatient and outpatient rotations, RT elective)
  1. Testicular Cancer:
  2. Be able to recognize clinical presentation
  3. Describe histopathology
  4. Be able to utilize tumor markers for clinical stating in nonseminomatous tumors
  5. Perform appropriate noninvasive imaging for post-orchiectomy staging
  6. Understand the role of retroperitoneal lymph node dissection vs. surveillance.
  7. Define the role of RT in post-op management of seminars
  8. Describe which patients with pure seminomas require chemotherapy
  9. Be able to list poor prognostic features associated with non-siminomatous tumors and utilize this to select appropriate chemotherapy
  10. Understand management of patients with PR or recurrent disease
  11. Describe complications of disease and treatment e.g. vascular, bleomycin palm toxicity
  1. Bladder Cancer:
  2. List risk factors for development of bladder cancer
  3. Describe the roles of surgery and intravesical treatment for patients with superficial bladder cancer
  4. Understand the surgical management of invasive cancer
  5. Understand the role of pre-and/or post-op radiation therapy
  6. Identify the patients who are appropriate candidates for neoadjuvant chemotherapy
  7. Understand the active chemotherapeutic regimens for metastatic disease and their response rates
  1. Prostate Cancer:

1.      Understand the use of PSA screening

  1. Understand the staging and histologic classification
  2. Utilize approach staging tests
  3. Identify patients who are appropriate for surgical management
  4. Describe the toxicities associated with total prostatectomy
  5. Describe the toxicity of radiation therapy
  6. Understand the role of hormone therapy in the management of prostate cancer and the available hormone manipulations
  7. Describe the pattern of metastasis
  1. Gynecologic Malignancies (Gyn elective, oncology inpatients, clinics,

elective)

  1. Ovarian Cancer:
  2. Pathology:  Know the different histologic subtypes of ovarian

cancer, epithelial and germ cell

  1. Understand the management of germ cell tumors and borderline

tumors

b. Cervical Cancer:

1.      Know the risk factors and the importance of herpes simplex virus and human papilloma virus

  1. Know the natural history and the patterns of spread
  2. Know the diagnostic procedures and the importance of screening (PAP)
  3. Know the standard clinical evaluation needed for preop staging.
  4. Know the FIGO staging of cervical cancer
  5. Understand the management of the different stages of disease and the role of radiation and surgery
  6. Understand the techniques and doses of radiation utilized in treatment
  7. Describe the expected response rates with chemotherapy and its role of palliative management
  1. Head and Neck Cancer (Lectures, outpatient clinics, RT elective, tumor board)
  2. Squamous Cell Carcinoma:

1.      Understand the anatomy and the different sites of origin of carcinoma

2.      Demonstrate the use of appropriate staging in the management.

3.      Know the roles of surgery and radiation in each of the different subtypes

  1. Understand the risks and benefits of larynx sparing surgery.

5.      Understand the role of neoadjuvant chemotherapy

  1. Thyroid Cancer:
  2. Understand the incidence and classification of thyroid cancer.
  3.    Know the TNM staging
  4. Know the risk factors for the development of thyroid cancer e.g.

goiter, RT

  1. Demonstrate how to evaluate a thyroid nodule with nonnative testing and

use of FNA

  1. Understand how to manage patients with well-differentiated thyroid cancer

and the prognosis (surgery, suppression, I-131)

  1. Sarcomas/Mesothelioma (Outpatient and inpatient rotations)
  2. Soft tissue sarcomas:
  3. Be able to distinguish between benign and malignant tumors.
  4. Understand the characteristics of different histologic subtypes and grading
  5. Discuss the role of surgery and radiation in the primary management
  6. Describe the chemotherapeutic agents that are active and the response rates in patients with metastatic disease
  1. Bone sarcomas:
  2. Understand the classification, staging and patters of spread
  3. Demonstrate knowledge of appropriate biopsy techniques
  4. Describe the role of neoadjuvant chemotherapy and adjuvant chemotherapy
  5. Understand the results of limb sparing surgical procedures
  6. Describe role of radiation therapy in management
  7. Understand the role of surgery in solitary metastatic pulmonary nodules
  8. Mesothelioma:
    1. Understand the association with asbestos and who is at risk for mesothelioma
    2. Know what biopsy procedures are available for diagnosis
    3. Understand the role of surgery, RT and chemotherapy in the management and the prognosis
  1. Complications of Malignancy (Lecture series, oncology rotation).
  2. Hospice – See Hospice Elective Goals and Objectives
  1. Pain Management – See Pain Management Elective Goals and Objectives
  1. Neutropenic Fever:

1.      Understand the common organisms which cause infection in the febrile neutropenic patient

  1. Know when and which antibiotics to start
  2. Understand the use of growth factors in the management of the neutropenic patient
  3. Know when to utilize antifungal therapy

 

 

PRACTICE BASED LEARNING

  1. Be able at outpatient clinic to use evidence based data regarding patient care.
  1. Regularly self-assesses his opinion on new patients and the opinion of the teaching faculty.

Looks at literature to decide on controversial issues

 

INTERPERSONAL SKILLS AND COMMUNICATIONS

  1. Demonstrate to teaching faculty an ability to honestly and in lay terms explain the prognosis to patients.
  2. Perform a psychosocial assessment of patients with cancer.
  3. Participate in counseling sessions attended by patients, family members and psychosocial professionals.
  1. Know how to utilize appropriate resources to assist patients and their families with coping

PROFESSIONALISM

 

  1. Be able to demonstrate a commitment to patients from diverse ethnic and

educational levels

  1. Responds appropriately to constructive criticism
  1. Demonstrates on “360” evaluations a thorough commitment to ethical

principal for our demographically diverse patient population

SYSTEM BASED PRACTICE

  1. Actively participates in rounds with the attending hematology/oncologists

and Inter Hospital Conferences